Browsing Bergen Open Research Archive by Author "O’Connell, Kevin"
Now showing items 1-2 of 2
-
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Hope, Sigrun; Shadrin, Alexey; Lin, Aihua; Bahrami, Shahram; Rødevand, Linn; Frei, Oleksandr; Hübenette, Saira Jameela; Cheng, Weiqiu; Hindley, Guy; Nag, Heidi Elisabeth; Ulstein, Line; Efrim-Budisteanu, Magdalena; O’Connell, Kevin; Dale, Anders; Djurovic, Srdjan; Nærland, Terje; Andreassen, Ole (Journal article; Peer reviewed, 2023)Autism spectrum disorder (ASD) is a highly heritable condition with a large variation in cognitive function. Here we investigated the shared genetic architecture between cognitive traits (intelligence (INT) and educational ... -
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits
Smith, Robert Løvsletten; O’Connell, Kevin; Athanasiu, Lavinia; Djurovic, Srdjan; Kringen, Marianne K.; Andreassen, Ole Andreas; Molden, Espen (Journal article; Peer reviewed, 2020)Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study (GWAS) of CLZ serum ...